Friday, 13 July 2012
Why HIV is not resisted by the human body
Researchers, have made a discovery which is described the
reason of fighting unabelity off HIV on human body. The researchers discovered
that the viral protein vpu, which is created by HIV during infection, directly
relates with the immune response protein IRF3 to dampen the ability of the
immune system to protect against HIV.
"By understanding exactly what HIV does to hamper
the innate immune response during early infection, we can develop a clearer
picture of how the virus is able to evade immunity to establish a long-term
infection," said Dr. Brian Doehle.
According to the earlier research result we are notified
that the virus bind with the IRF3 cells and suppress our immunity system.
The new studies found that the HIV protein vpu
specifically binds to the immune protein IRF3 and targets it for destruction.
So the prevention of IRF3 from HIV virus destruction is the best way to blocked
HIV spreding.The scientists also found that HIV strains engineered to lack vpu,
which is made during infection, did not impair the immune response.
"We have effectively identified a new Achilles heel
in the arsenal that HIV uses to overcome the defenses present in the body's
immune system", stated Dr. Gale.As per the information the best proses is
designing a new HIV antiviral therapeutics that prevent vpu from interacting
with IRF3 and targeting it for destruction. Even though HIV antiviral
therapeutics have already been developed and can effectively treat HIV
infections.
UW Medical Scientist Training Program has developed a
procedure to measure IRF3 activity in human blood cells. This new methodology
will be used to measure IRF3 function over the pathogenic condition of HIV
infection from the early stages of acute
infection to the later stages of chronic infection that lead to AIDS.
so we are hoped that now
the mortal HIV will be in control of human hand.
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1 Responses to “ Why HIV is not resisted by the human body ”
10 October 2013 at 21:09
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